Redox-responsive polymers for drug delivery: from molecular design to applications

• DOI: 10.1039/c3py01192e
• Publication Date: 2013-10-29T16:16:49Z
• Authors: Meng Huo; Jinying Yuan; Lei Tao; Yen Wei
• Keywords: 02 engineering and technology; 0210 nano-technology; 3. Good health

Glutathione has been regarded as a significant signal for distinguishing between tumor and normal tissue. Recently, reactive oxygen species have attracted much attention their close connection with many diseases. Taking advantage of the physiological signals, redox-responsive polymeric drug carriers constitute research area in various stimuli-responsive polymers biomedical applications. During rapid development polymers, molecular design related synthetic methodology plays crucial role. In this review, we discuss reduction- oxidation-responsive from view functional groups, well applications controlled release.