Protein synthesis in artificial cells: using compartmentalisation for spatial organisation in vesicle bioreactors

• DOI: 10.1039/c4cp05933f
• Publication Date: 2015-05-01T15:30:16Z
• Authors: Yuval Elani; Robert V. Law; Oscar Ces
• Keywords: Artificial cell; Chassis; Synthetic Biology; Compartment (ship)

Whereas spatial organisation of function is ubiquitous in biology, it has been lacking artificial cells. We rectify this by using multi-compartment vesicles as chassis for cells, allowing distinct biological processes to be isolated space. This demonstrated vitro synthesis two proteins predefined vesicle regions.