A new class of high-contrast Fe(ii) selective fluorescent probes based on spirocyclized scaffolds for visualization of intracellular labile iron delivered by transferrin

• DOI: 10.1039/c4ob00935e
• Publication Date: 2014-06-03T13:46:09Z
• Authors: Masato Niwa; Tasuku Hirayama; Kensuke Okuda; Hideko Nagasawa
• Keywords: 0301 basic medicine; Cytoplasm; Ion Transport; Cations, Divalent; Rhodamines; Iron; Transferrin; Hep G2 Cells; Iron Chelating Agents; Endocytosis; Molecular Imaging; 03 medical and health sciences; Spectrometry, Fluorescence; Humans; Spiro Compounds; Lysosomes; Fluorescent Dyes

A new class of high-contrast Fe(ii) selective fluorescent probes based on spirocyclized scaffolds were developed to visualize transferrin-delivered intracellular labile iron.