A simple and automated online SPE-LC-MS/MS method for simultaneous determination of olanzapine, fluoxetine and norfluoxetine in human plasma and its application in therapeutic drug monitoring

Therapeutic Drug Monitoring Quality by Design Sample Preparation
DOI: 10.1039/c5ra02489g Publication Date: 2015-04-08T08:32:46Z
ABSTRACT
An integration of sample pretreatment automation using online SPE technique could provide an easy to use, efficient, sensitive and high quality methods for TDM.
SUPPLEMENTAL MATERIAL
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