Palladium-catalyzed ligand-free and efficient Suzuki–Miyaura reaction of heteroaryl halides with MIDA boronates in water

• DOI: 10.1039/c5ra10001a
• Publication Date: 2015-06-15T12:30:46Z
• Authors: Chun Liu; Xinmin Li; Chao Liu; Xinnan Wang; Jieshan Qiu
• Keywords: 01 natural sciences; 0104 chemical sciences

A simple and environment-friendly protocol for the palladium-catalyzed Suzuki–Miyaura reaction of heteroaryl halides with N-methyliminodiacetic acid (MIDA) boronates in pure water is developed.