Synthesis of 3-fluoroalkenyl-3-trifluoromethyl-2-oxindoles by the reaction of indoline-2,3-diones with difluoromethylene phosphabetaine

• DOI: 10.1039/c6cc00666c
• Publication Date: 2016-03-30T19:51:52Z
• Authors: Yingle Liu; Ke Zhang; Yangen Huang; Shen Pan; Xiao-Qiang Liu; Yi Yang; Yan Jiang; Xiu-Hua Xu
• Keywords: Betaine; Indoles; Chemistry Techniques, Synthetic; 01 natural sciences; Catalysis; Oxindoles; 0104 chemical sciences

The reaction of indoline-2,3-diones and (triphenylphosphonio)difluoroacetate (PDFA) afforded novel 3-fluoroalkenyl-3-trifluoromethyl-2-oxindoles in moderate to excellent yields.