Selective reduction of carboxylic acids to aldehydes with hydrosilane via photoredox catalysis

• DOI: 10.1039/c7cc05570f
• Publication Date: 2017-08-18T11:25:38Z
• Authors: Muliang Zhang; Nan Li; Xingyu Tao; Rehanguli Ruzi; Shouyun Yu; Chengjian Zhu
• Keywords: Amide; Photoredox catalysis; Alkyne; Functional group; Selective Reduction; Hydrogen atom

The direct reduction of carboxylic acids to aldehydes with hydrosilane was achieved through visible light photoredox catalysis. combination both single electron transfer and hydrogen atom steps offers a novel convenient approach selective aldehydes. method also features mild conditions, high yields, broad substrate scope, good functional group tolerance, such as alkyne, ester, ketone, amide amine groups.