Binding properties of mono- and dimeric pyridine dicarboxamide ligands to human telomeric higher-order G-quadruplex structures

• DOI: 10.1039/c7cc07048a
• Publication Date: 2018-01-30T11:34:14Z
• Authors: C. Saintomé; P. Alberti; N. Guinot; P. Lejault; J. Chatain; P. Mailliet; J.-F. Riou; A. Bugaut
• Keywords: G-quadruplex

A new dimeric ligand binds telomeric contiguous G4s, displacing the single-stranded DNA binding RPA more efficiently than its monomeric counterpart.