Neuroprotective action of tea polyphenols on oxidative stress-induced apoptosis through the activation of the TrkB/CREB/BDNF pathway and Keap1/Nrf2 signaling pathway in SH-SY5Y cells and mice brain

• DOI: 10.1039/c7fo00991g
• Publication Date: 2017-10-05T09:33:04Z
• Authors: Guoyuan Qi; Yashi Mi; Yiwen Wang; Runnan Li; Shuxian Huang; Xingyu Li; Xuebo Liu
• Keywords: Male; Neurons; 0301 basic medicine; Kelch-Like ECH-Associated Protein 1; Cell Survival; NF-E2-Related Factor 2; Plant Extracts; Brain-Derived Neurotrophic Factor; Brain; Polyphenols; Apoptosis; CREB-Binding Protein; Camellia sinensis; 3. Good health; Mice, Inbred C57BL; Mice; Oxidative Stress; 03 medical and health sciences; Neuroprotective Agents; Animals; Humans; Receptor, trkB; Signal Transduction

Neuroprotective effects of tea polyphenols on apoptosis and oxidative stress induced by constant darkness and H2O2in vivoandin vitro.