Branched BBB-shuttle peptides: chemoselective modification of proteins to enhance blood–brain barrier transport

• DOI: 10.1039/c8sc02415d
• Publication Date: 2018-09-18T10:03:59Z
• Authors: Cristina Díaz-Perlas; Benjamí Oller-Salvia; Macarena Sánchez-...; Meritxell Teixidó; Ernest Giralt
• Keywords: 0301 basic medicine; Chemistry; 03 medical and health sciences

THRre is a protease resistant BBB-shuttle. A branched version of displaying two copies the peptide increases transport model protein in BBB cell-based models.