A molecular recognition-activatable DNA nanofirecracker enables signal-enhanced imaging in living cells

SIGNAL (programming language) Molecular Recognition
DOI: 10.1039/c9cc09682e Publication Date: 2020-01-30T14:23:40Z
ABSTRACT
We propose an aptamer-tethered DNA nanofirecracker probe that realizes molecular recognition-activatable disassembly of the nanostructure for imaging target molecules in living cells. The design principle offers a new paradigm to develop nucleic acid nanocircuits live-cell study and manipulation.
SUPPLEMENTAL MATERIAL
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