PdII-Catalyzed methoxylation of C(sp3)–H bonds adjacent to benzoxazoles and benzothiazoles

• DOI: 10.1039/c9ob00337a
• Publication Date: 2019-03-06T13:23:05Z
• Authors: Jogendra Kumar; Aniket Gupta; Sukalyan Bhadra
• Keywords: Benzoxazole; Benzothiazole; Azole

Benzoxazoles and benzothiazoles govern the Pd^II-catalyzed regiospecific methoxylation of proximal-selective α-C(sp³)–H bond to access α-methoxyacetic acids <italic>O</italic>-methylated Breslow intermediates.