A rapid and sensitive CRISPR/Cas12a based lateral flow biosensor for the detection of Epstein–Barr virus

• DOI: 10.1039/d0an00663g
• Publication Date: 2020-07-30T10:53:35Z
• Authors: Ting Yuan; Omar Mukama; Zhiyuan Li; Wei Chen; Yuxia Zhang; Jean de Dieu Habi...; Yinghui Zhang; Rong Zeng; Chengrong Nie; Zhixu He; Lingwen Zeng
• Keywords: 0301 basic medicine; Epstein-Barr Virus Infections; Herpesvirus 4, Human; 03 medical and health sciences; DNA, Viral; Humans; Clustered Regularly Interspaced Short Palindromic Repeats; Nasopharyngeal Neoplasms; Biosensing Techniques; CRISPR-Cas Systems; 3. Good health

In this study, we developed a simple and sensitive approach for EBV detection. The assay attained a high specificity in the presence of various bacteria and applicability in EBV Burkitt's lymphoma serum samples.