Enhanced solubility, permeability, and tabletability of nicorandil by salt and cocrystal formation

• DOI: 10.1039/d0ce01316a
• Publication Date: 2020-11-03T09:03:19Z
• Authors: M. K. Chaitanya M...; Anilkumar Gunnam; Anurag Lodagekar; Nalini R. Shastri; Ashwini K. Nangia; K. Anand Solomon
• Keywords: Cocrystal; Nicorandil; Crystal Engineering; Rational design

Cocrystallization is a rational selection crystal engineering approach for the development of novel solid forms with enhanced physicochemical and mechanical properties.