Oral administration of EGCG solution equivalent to daily achievable dosages of regular tea drinkers effectively suppresses miR483-3p induced metastasis of hepatocellular carcinoma cells in mice

• DOI: 10.1039/d1fo00664a
• Publication Date: 2021-03-16T12:18:43Z
• Authors: Qingzheng Kang; Yin Tong; Vemana Gowd; Mingfu Wang; Feng Chen; Ka-Wing Cheng
• Keywords: Mice, Inbred BALB C; 0303 health sciences; Carcinoma, Hepatocellular; Tea; Liver Neoplasms; Mice, Nude; Hep G2 Cells; Catechin; 3. Good health; Gene Expression Regulation, Neoplastic; Solutions; Mice; MicroRNAs; 03 medical and health sciences; Transduction, Genetic; Cell Line, Tumor; Animals; Humans; Female; Neoplasm Metastasis; Reactive Oxygen Species

EGCG suppresses miR483-3p induced metastasis of HCC cells through epigenetic modulation of miR483-3p expression and antioxidation.