A practical and sustainable protocol for direct amidation of unactivated esters under transition-metal-free and solvent-free conditions

• DOI: 10.1039/d1gc00720c
• Publication Date: 2021-04-21T20:29:55Z
• Authors: Rui Zhang; Wei-Zhong Yao; Liang Qian; Wei Sang; Ye Yuan; Min-Chen Du; Hua Cheng; Cheng Chen; Xin Qin
• Keywords: 01 natural sciences; 6. Clean water; 0104 chemical sciences; 12. Responsible consumption

An environmentally friendly and scalable protocol was developed for direct amidation of unactivated esters under transition-metal-free, solvent-free and chromatography-free conditions.