Seventeen novel angiotensin converting enzyme (ACE) inhibitory peptides from the protein hydrolysate ofMytilus edulis: isolation, identification, molecular docking study, and protective function on HUVECs

• DOI: 10.1039/d2fo00275b
• Publication Date: 2022-06-16T00:21:10Z
• Authors: Shi-Kun Suo; Yu-Qin Zhao; Yu-Mei Wang; Xiao-Yang Pan; Chang-Feng Chi; Bin Wang
• Keywords: 0301 basic medicine; Mytilus edulis; Protein Hydrolysates; Angiotensin-Converting Enzyme Inhibitors; Hydrogen Peroxide; Peptidyl-Dipeptidase A; Nitric Oxide; 3. Good health; Molecular Docking Simulation; 03 medical and health sciences; Human Umbilical Vein Endothelial Cells; Animals; Humans; Peptides

This study suggested that bioactive peptides from blue mussel could serve as a therapeutic alternative in the treatment of hypertension because of their ACE inhibitory activity and protective effects on oxidative damaged HUVECs.