Exploring the molecular structure of lipids in the design of artificial lipidated antifungal proteins

• DOI: 10.1039/d3pm00087g
• Publication Date: 2024-05-24T16:17:43Z
• Authors: Hendra Saputra; Muhammad Safaat; Kazuki Uchida; Pugoh Santoso; Rie Wakabayashi; Masahiro Goto; Toki Taira; Noriho Kamiya
• Keywords: 0303 health sciences; 03 medical and health sciences

The antifungal activity of a small chitin-binding domain from chitinase was enhanced by the artificial lipidation with specific alkyl chain length and structure in presence amphotericin B.