A scalable synthesis of adjuvanting antigen depots based on metal–organic frameworks

• DOI: 10.1039/d3sc06734c
• Publication Date: 2024-01-24T10:02:10Z
• Authors: Ryanne N. Ehrman; Olivia R. Brohlin; Yalini H. Wijesun...; Sneha Kumari; Orikeda Trashi; Thomas S. Howlett; Ikeda Trashi; Fabian C. Herbert; Arun Raja; Shailendra Koirala; Nancy Tran; Noora M. Al-Kharji; Wendy Tang; Milinda C. Senara...; Laurel M. Hagge; Ronald A. Smaldone; Jeremiah J. Gasse...

ZIF-8 vaccine enhances the humoral immune response through sustained antigen exposure to the immune system whilst zinc adjuvants the vaccine via inducing T cell activation.