Novel fused pyran derivatives induce apoptosis and target cell cycle progression in anticancer efficacy against multiple cell lines

• DOI: 10.1039/d4nj00824c
• Publication Date: 2024-03-19T11:41:58Z
• Authors: K. Fabitha; Anoop Kallingal; Natalia Maciejewska; C. G. Arya; Munugala Chandrak...; Neethu Mariam Thomas; Yupeng Li; Ramesh Gondru; Manne Munikumar; Janardhan Banothu
• Keywords: Pyran; Benzotriazole; Imidazole; Benzimidazole; Pyrazole; Triazole

Nitrogen-based heterocycles substituted fused pyran derivatives (6a–e, 8a–e, 10a–e, 12a–e, & 14a–e) have been synthesized and tested for their in vitro anticancer efficacies against MCF7, A549, HCT116 cancer cell lines.