One-pot synthesis of E-chalcones using a multifunctional catalyst comprised of ruthenium nanoparticles and palladium N-heterocyclic carbene complexes immobilized on silica

• DOI: 10.1039/d4sc07773c
• Publication Date: 2025-03-12T11:02:14Z
• Authors: Manisha Durai; Yufei Wu; Jacob Johny; Walid Hetaba; Thomas Wiegand; Walter Leitner; Alexis Bordet

The one-pot synthesis of valuable E-chalcones is achieved using a multifunctional Ru@SiO2-[Pd–NHC] catalytic system combining molecular and nanoparticle sites for efficient carbonylative Sonogashira coupling and selective hydrogenation.