Photoradiolabeling of onartuzumab with 99mTc and 188Re-tricarbonyl for radiotheranostics of gastric cancer

• DOI: 10.1039/d4sc08089k
• Publication Date: 2025-03-13T09:00:38Z
• Authors: Jonas Genz; Cesare Berton; Samy Kichou; Simon Klingler; Mirja C. Nolff; Henrik Braband; Jason P. Holland

Light-induced bioconjugation and radiolabeling of the cancer-specific monoclonal antibody onartuzumab was accomplished using the tricarbonyl chemistry of the radiotheranostic matched pair of nuclides 99mTc and 188Re.