Architectural control of rod-coil block polypeptide thermoresponsive self-assembly via de novo design of coiled-coil orientation

• DOI: 10.1039/d4tb02420f
• Publication Date: 2025-03-14T13:02:10Z
• Authors: Bin Wang; Weiran Xie; Tianren Zhang; Darrin Pochan; Jeffrey Saven; Kristi Kiick

The architectural control of the self-assembly of a series of block polypeptides comprising a concatenation of an elastin-like peptide and a coiled-coil, bundle-forming peptide (ELP-BFPs), has been demonstrated. Assembly of...