A practical one-pot synthesis of dehydroalanine esters

• DOI: 10.1039/d5ra00035a
• Publication Date: 2025-03-27T08:40:20Z
• Authors: Qingyuan Shi; Mengxiao Zhu; Zhenchu Liang; Xu Dong; Minyue Zhang; Lili Yang; Pingping Sun; Chuanyi Xing; Xiaohao Zha; Fei Li; Hongliang He; Dongyin Chen

A practical one-pot synthesis of various dehydroalanine esters was realized via a Cs2CO3-mediated simultaneous esterification/elimination process, starting from commercially available N-protected serines and various haloalkanes.