Exploring a solid-state nanopore approach for single-molecule protein detection from single cells

• DOI: 10.1039/d5sc01764e
• Publication Date: 2025-04-07T08:29:35Z
• Authors: Zi-Qi Zhou; Shao-Chuang Liu; Jia Wang; Ke-Le Chen; Bao-Kang Xie; Yi-Lun Ying; Yi-Tao Long

This study presents a solid-state nanopore approach for single-molecule protein detection from single cells, utilizing a nanopore electrophoretic driver protein to enhance target protein capture efficiency and analyze protein conformational changes.