Maternal‐Fetal Hemorrhage: A Reappraisal

• DOI: 10.1046/j.1423-0410.1996.7120103.x
• Publication Date: 2003-05-15T08:33:48Z
• Authors: Y. Brossard; J. C. Pons; I. Jrad; J. van Nifterik; R. Gillot; C. Saure; M. Le Gaudion; A. Richard; E. Papiernik
• Keywords: Adult; 03 medical and health sciences; Erythrocytes; 0302 clinical medicine; Pregnancy; Pregnancy Complications, Hematologic; Infant, Newborn; Humans; Female; Maternal-Fetal Exchange; 3. Good health

To determine the frequency of maternal-fetal hemorrhage at or above 1 microliter maternal whole blood.Seventy-three mothers whose red blood cells bore an Rh antigen (Rh D, c, E) that was absent on their newborns were identified and a new cytological method, Kleihauerimmunogold-silver-staining technique, applied neonates to detect quantify cells. Stringent precautions taken avoid contaminations neonatal samples by adult cells.Maternal present in 3 newborns, 4% (95% Cl: 1-11%), estimated volumes 0.8, 1.5, 101 microliters blood. No obstetric factor clearly associated this limited study with occurrence hemorrhage.Mother-to-fetus microtransfusion greater than is infrequent near delivery, it may be observed after uncomplicated pregnancy vaginal delivery.