Inexpensive, universal serial bus-powered and fully portable lab-on-a-chip-based capillary electrophoresis instrument

• DOI: 10.1049/iet-nbt:20080005
• Publication Date: 2009-02-16T23:17:17Z
• Authors: G.V. Kaigala; M. Behnam; C. Bliss; M. Khorasani; S. Ho; J.N. McMullin; D.G. Elliott; C.J. Backhouse
• Keywords: Interfacing; Lab-on-a-Chip; Microelectronics; Implementation

Capillary electrophoresis is a cornerstone of lab-on-a-chip (LOC) implementations for medical diagnostics. However, the infrastructure needed to operate electrophoretic LOC tends be large and expensive, hindering development portable or low-cost systems. A custom-designed highly integrated microelectronic chip high-voltage generation switching interfacing recently developed. Here, authors integrate with microfluidic chip, solid-state laser, filter, lens several dollars worth electronic components form an inexpensive platform, which size mobile telephone. This compact system has such reduced power requirements that complete platform can operated using universal serial bus link computer. It believed this represents significant advancement in practical point-of-care