Immune and Inflammatory Response in Atopic Elite Endurance Athletes

• DOI: 10.1055/a-0633-9001
• Publication Date: 2018-06-25T23:34:20Z
• Authors: Renata Teixeira; Gerson dos Santos...; Renata Gorjao; Patricia Palmeira; Cesar Santos; Raquel Zambonatto; Heloisa de Oliveira; Adriana Levada; Iara Fiks; Celso Carvalho
• Keywords: Atopy; Elite Athletes

Abstract The present study aimed to compare the immune and inflammatory responses between atopic (n=20) non-atopic (n=39) elite endurance athletes. Fifty-nine runners triathletes were assessed for following measurements: Th1, Th2 lymphocyte phenotyping plasma levels of cortisol, chemokines, cytokines specific immunoglobulin E (IgE). Levels salivary IgA, allergic symptoms training data also evaluated. No difference was observed in baseline levels. However, Th1 lymphocytes athletes presented a lower response after activation. In contrast this result, IgA CXCL9 chemokine higher It that volume per week linearly associated with levels, IgE addition, linear multiple regression analysis demonstrated only factor (r=0.53; p=0.04). These results suggest compared athletes, reduced IgA. Training is symptoms, which suggests they may play role atopy