Upfront Nephrectomy for the Treatment of Wilms Tumor: Outcomes and Predictors of Complications

• DOI: 10.1055/s-0038-1641149
• Publication Date: 2018-04-13T18:42:45Z
• Authors: Lucas Krauel; Irene de Haro; Rosalia Carrasco; Margarita Vancells; Jaume Mora
• Keywords: Anaplasia; Medical record

Wilms tumor (WT) is the most common kidney in children. Upfront nephrectomy and preoperative chemotherapy, two different treatment strategies, have not shown considerable differences outcomes. Research focus has turned into decreasing incidences of posttreatment morbidity. The aim this study to determine existence prognostic factors predictors surgical complications with upfront surgery following COG protocol. Medical records patients WT treated between 2003 2013 were retrospectively reviewed focusing on aspects complications. Forty-five identified. mean age at diagnosis was 3.8 years (2–154 months). Thirteen them had stage I disease (28.9%), 12 II (26.7%), 15 III (33.3%), 5 IV (11.1%). Mean follow-up 4.5 (2–132 4-year overall survival (OS) event-free (EFS) 100 91.1%, respectively. There 4 cases progression (3 lung 1 locoregional relapse). We intraoperative rupture (4.4%), one partial colectomy, a distal pancreatectomy. complication associated blood transfusion (44.4%). anaplasia risk factor for (p = 0.01). Clinical size positively correlated 0.001); relationship observed other are progression. Standardized scales such as Clavien–Dindo should be used properly compare outcomes approaches.