Regioselective Synthesis of Thieno[2,3-b]quinolin-4(9H)-ones: Occurrence of Thermal [1,3] Sigmatropic Rearrangement.

• DOI: 10.1055/s-2002-23545
• Publication Date: 2002-07-26T11:47:25Z
• Authors: K. Majumdar; M. Ghosh; M. Jana
• Keywords: 01 natural sciences; 0104 chemical sciences

A number of hitherto unreported thieno[2,3-b]quinolin-4(9H)-ones 5a-f have been regioselectively synthesized from the corresponding 4-(prop-2-ynyloxy)quinolin-2(1H)-thiones 4a-f. The 4-(Prop-2-ynyloxy)quinolin-2(1H)-thiones 4a-f were prepared by thionation 4-(prop-2-ynyloxy)quinolin-2(1H)-ones 3a-f. latter compounds in turn alkylation 4-hydroxyquinolin-2(1H)-one (1).