The Synthesis of Fluorescent DNA Intercalator Precursors through Efficient Multiple Heck Reactions

• DOI: 10.1071/ch10374
• Publication Date: 2011-03-11T03:10:06Z
• Authors: Nigel A. Lengkeek; Ramiz A. Boulos; Allan J. McKinley; Thomas V. Riley; Boris Martinac; Scott G. Stewart
• Keywords: Heck Reaction; Biocatalysis; Coupling reaction

A highly efficient synthesis of p-carboethoxy-tristyryl and carboethoxy-terastyrenyl benzene derivatives through a multiple Heck cross coupling reaction is reported. This provides an route to DNA intercalator precursors containing core.