Comparative transcriptomics reveals patterns of selection in domesticated and wild tomato

• DOI: 10.1073/pnas.1309606110
• Publication Date: 2013-06-27T04:36:03Z
• Authors: Daniel Koenig; José M. Jiménez-G...; Seisuke Kimura; Daniel Fulop; Daniel H. Chitwood; Lauren R. Headland; Ravi Kumar; Michael F. Covington; Upendra Kumar Dev...; An V. Tat; Takayuki Tohge; Anthony Bolger; Korbinian Schneeb...; Stephan Ossowski; Christa Lanz; Guangyan Xiong; Mallorie Taylor-T...; Siobhan M. Brady; Markus Pauly; Detlef Weigel; Björn Usadel; Alisdair R. Fernie; Jie Peng; Neelima R. Sinha; Julin N. Maloof
• Keywords: 2. Zero hunger; domestication; 0303 health sciences; 03 medical and health sciences; abiotic stress; biotic stress; Solanum lycopersicum; Gene Expression Regulation, Plant; [SDV]Life Sciences [q-bio]; Selection, Genetic; Genes, Plant; Transcriptome

Significance One of the most important technological advances by humans is the domestication of plant species for the production of food. We have used high-throughput sequencing to identify changes in DNA sequence and gene expression that differentiate cultivated tomato and its wild relatives. We also identify hundreds of candidate genes that have evolved new protein sequences or have changed expression levels in response to natural selection in wild tomato relatives. Taken together, our analyses provide a snapshot of genome evolution under artificial and natural conditions.