Participation of a DNA-RNA hybrid complex in in vivo genetic transcription.

• DOI: 10.1073/pnas.55.3.635
• Publication Date: 2006-05-31T05:45:07Z
• Authors: M N Hayashi; M Hayashi
• Keywords: Transcription; 30S; Peptidyl transferase; 50S

The ribosome is a macromolecular machine that undergoes global conformational rearrangements during translation, involve coupled movements of ribosomal subunits, tRNAs, and the L1 stalk. However, there disagreement between different ...The two main steps peptidyl transfer, translocation are accompanied by counterclockwise clockwise rotations large small subunits with respect to each other. Upon subunit ...