Evolution of asymmetric proptosis during the active phase of thyroid eye disease

• DOI: 10.1080/01676830.2022.2088807
• Publication Date: 2022-07-08T11:11:03Z
• Authors: Ann Q. Tran; Henry W. Zhou; Tavish Nanda; Kyle J. Godfrey; Andrea A. Tooley; Victoria S. North; Michael Kazim
• Keywords: Graves Ophthalmopathy; 03 medical and health sciences; 0302 clinical medicine; Humans; Exophthalmos; Postoperative Period; Decompression, Surgical; Retrospective Studies; 3. Good health

Purpose To assess the evolution of proptosis asymmetry during active phase bilateral thyroid eye disease (TED).Methods A retrospective study was conducted on patients with bilateral, TED. Patients were measured by a single observer, using Hertel exophthalmometry from time initial presentation, TED, to stable phase, 24-months later. Asymmetric defined as >2 mm intra-orbital difference in measurements.Results Fifty-one enrolled. presented at mean 1.1 ± 2.9 months following onset TED symptoms. Stability established 15.7 12.3 months. At 41% demonstrated asymmetric proptosis. Upon reaching persisted only 22% patients. decline rate greatest within first 3 phase.Conclusions is common setting early and decreases 50% when reached. Therefore, diagnostic imaging not routinely required exclude alternative pathology cases Perhaps more importantly, this finding supports surgical paradigm graded orbital decompression, performed ultimate globe positions are achieved avoid late postoperative asymmetry, resulting unanticipated surgery