Massive Sodium Nitrite Overdose: A Case for Prehospital Methylene Blue

• DOI: 10.1080/10903127.2024.2357597
• Publication Date: 2024-05-23T19:23:22Z
• Authors: Carlos A. Garcia-...; Lesley C. Pepin; Travis D. Olives; Jon B. Cole; Holly M. Drone; Gregg A. Jones; Nicholas S. Simpson; Ryan T. Fuchs; Aaron E. Robinson
• Keywords: Methemoglobinemia; Sodium nitrite; Antidote; Methylene blue

Sodium nitrite overdose leads to profound methemoglobinemia and may quickly progress death. It is an increasingly common method of suicide often fatal. Methylene blue effective but time-sensitive antidote that has the potential save lives when administered early. In this case report, we describe a fatal sodium subsequent creation prehospital protocol for our large urban Emergency Medical Services system.