The Association between Body Mass Index and Osteoporosis in Patients Referred for a Bone Mineral Density Examination

• DOI: 10.1089/jwh.2006.15.1028
• Publication Date: 2006-11-24T18:39:29Z
• Authors: Kofi Asomaning; Elizabeth R. Bert...; Philip C. Nasca; Frederick Hooven; Penelope S. Pekow
• Keywords: Adult; Aged, 80 and over; 2. Zero hunger; 0301 basic medicine; Middle Aged; United States; Body Mass Index; 3. Good health; 03 medical and health sciences; Absorptiometry, Photon; Cross-Sectional Studies; Thinness; Bone Density; Risk Factors; Confidence Intervals; Odds Ratio; Humans; Women's Health; Female; Osteoporosis, Postmenopausal; Aged

Osteoporosis affects 4-6 million (13%-18%) postmenopausal white women in the United States. Most studies to date on risk factors for osteoporosis have considered body mass index (BMI) only as a possible confounder. In this study, we assess direct relationship between BMI and osteoporosis.We conducted cross-sectional study among aged 50-84 years referred by their physicians bone mineral density (BMD) examination at Baystate Medical Center October 1998 September 2000. was determined prior BMD clinic. Information other obtained through mailed questionnaire. Ordinal logistic regression used model association osteoporosis, controlling confounding factors.BMI inversely associated with status. After adjustment age, hormone replacement therapy (HRT) use, factors, odds ratios (OR) low, high, obese compared moderate were 1.8 (95% CI 1.2-2.7), 0.46 0.29- 0.71), 0.22 0.14-0.36), respectively, significant linear trend (p < 0.0001) across categories. Evaluating continuous variable, of loss decreased 12% each unit increase (OR = 0.88, 95% 0.85-0.91).Women low are increased osteoporosis. The change 1 ( approximately 5-8 lb) is greater magnitude than most modifiable factors. To help reduce patients should be advised maintain normal weight.