Comparison Between Continuous Brain Tissue pO2, pCO2, pH, and Temperature and Simultaneous Cerebrovenous Measurement Using a Multisensor Probe in a Porcine Intracranial Pressure Model

• DOI: 10.1089/neu.1998.15.265
• Publication Date: 2009-01-30T07:38:31Z
• Authors: M. MENZEL; A. RIEGER; S. ROTH; J. SOUKUP; I. FURKA; I. MIKO; P. MOLNAR; C. PEUSE; C. HENNIG; J. RADKE
• Keywords: Brain tissue; pCO2

Local brain tissue oxygenation (ptiO2) and global cerebrovenous hemoglobin saturation (SJO2) are increasingly used to continuously monitor patients after severe head injury (SHI). In patients, simultaneous local oxygen measurements of these types have shown different results regarding the comparability findings during changes in CPP ICP. This is contrast theoretical expectations. The aim this study was compare PtiO2 measurement with partial pressure (pcvO2) an animal intracranial model. To end, a multisensor probe placed left frontoparietal white matter measure ptiO2, pCO2 (ptiCO2), pH (pHti), temperature (tti) while simultaneously measuring same parameters (pcvO2, pcvCO2, pHcv, tcv) sagittal sinus 9 pigs under general anesthesia. By stepwise inflating balloon catheter, supracerebellar infratentorial compartment, ICP increased decreased. baseline levels ptiCO2, pHti noninjured showed more heterogeneity compared blood. Both, ptiO2 pcvO2 were significantly correlated induced decrease. PCO2 inversely course both compartments. Temperature positive correlation These demonstrate that oximetry pO2 sensitive changes. newly available continuous probes could be helpful interpreting cerebral man by analyzing interrelationship parameters.