The Effect of Cranioplasty on Cerebral Hemodynamics as Measured by Perfusion Computed Tomography and Doppler Ultrasonography

• DOI: 10.1089/neu.2015.4261
• Publication Date: 2015-11-06T05:23:43Z
• Authors: Igor Paredes; Ana María Castaño; Santiago Cepeda; Jose Antonio Fern...; Elena Salvador; Jose María Millán; Alfonso Lagares
• Keywords: Cranioplasty

Cranioplasties are performed to protect the brain and correct cosmetic defects, but there is growing evidence that this procedure may result in neurological improvement. We prospectively studied cranioplasties at our hospital over a 5-year period. The National Institute of Health Stroke Scale Barthel index were recorded prior within 72 h after cranioplasty. A perfusion computed tomography (PCT) transcranial Doppler sonography (TCDS) surgery. For PCT, regions irrigated by anterior cerebral artery, middle artery (MCA), posterior basal ganglia selected, as well mean values for hemisphere. was sitting supine position MCA internal carotid. velocities, pulsatility index, resistance Lindegaard ratio (LR) obtained, variation value LR (ΔLR = - supine). Fifty-four patients included study. Of these, 23 (42.6%) presented with objective blood flow defective side (m-CBF-d) increased from 101.86 117.17 mL/100 g/min (p 0.064), m-CBF healthy (m-CBF-h) 128.14 145.73 0.028). With regard TCDS, ΔLR greater on surgery those who showed improvement (1.295 vs. -0.714; p 0.002). Cranioplasty resulted clinical 40% patients, an increase post-surgical CBF. larger variations when patient moved might predict