JOY: protein sequence-structure representation and analysis.

• DOI: 10.1093/bioinformatics/14.7.617
• Publication Date: 2002-07-26T22:40:04Z
• Authors: K Mizuguchi; C M Deane; T L Blundell; M S Johnson; J P Overington
• Keywords: Representation; Sequence (biology); Multiple sequence alignment

Abstract MOTIVATION: JOY is a program to annotate protein sequence alignments with three-dimensional (3D) structural features. It was developed display 3D information in alignment and help understand the conservation of amino acids their specific local environments. RESULTS:: The representation now constitutes an essential part two databases structure alignments: HOMSTRAD (http://www-cryst.bioc.cam.ac.uk/homstrad ) CAMPASS (http://www-cryst.bioc.cam.ac. uk/campass). has also been successfully used for identifying distant evolutionary relationships. AVAILABILITY: can be obtained via anonymous ftp from torsa.bioc.cam.ac.uk directory /pub/joy/. address server http://www-cryst.bioc.cam.ac.uk/cgi-bin/joy.cgi. CONTACT: [e-mail]