Geno3D: automatic comparative molecular modelling of protein

• DOI: 10.1093/bioinformatics/18.1.213
• Publication Date: 2002-07-26T18:37:51Z
• Authors: Christophe Combet; Martin Jambon; Gilbert Deléage; Christophe Geourjon
• Keywords: Dihedral angle; Template; Homology; Sequence homology; Protein structure database; Protein superfamily

Abstract Geno3D (http://geno3d-pbil.ibcp.fr) is an automatic web server for protein molecular modelling. Starting with a query sequence, the performs homology modelling in six successive steps: (i) identify homologous proteins known 3D structures by using PSI-BLAST; (ii) provide user all potential templates through very convenient interface target selection; (iii) perform alignment of both and subject sequences; (iv) extract geometrical restraints (dihedral angles distances) corresponding atoms between template; (v) construction distance geometry approach (vi) finally send results e-mail to user. Availability: Free academic users http://geno3d-pbil.ibcp.fr Contact: [e-mail] * To whom correspondence should be addressed.