NaViA: a program for the visual analysis of complex mass spectra

• DOI: 10.1093/bioinformatics/btab436
• Publication Date: 2021-06-17T11:12:13Z
• Authors: Daniel Quetschlich; Tim K Esser; Thomas D Newport; Francesco Fiorentino; Denis Shutin; Siyun Chen; Rachel Davis; Silvia Lovera; Idlir Liko; Phillip J Stansfeld; Carol V Robinson
• Keywords: Stoichiometry

Native mass spectrometry is now a well-established method for the investigation of protein complexes, specifically their subunit stoichiometry and ligand binding properties. Recent advances allowing analysis complex mixtures lead to an increasing diversity complexity in spectra obtained. These can be time-consuming tackle through manual assignment challenging automated approaches.