MeRIPseqPipe: an integrated analysis pipeline for MeRIP-seq data based on Nextflow

• DOI: 10.1093/bioinformatics/btac025
• Publication Date: 2022-01-10T20:11:14Z
• Authors: Xiaoqiong Bao; Kaiyu Zhu; Xuefei Liu; Zhihang Chen; Ziwei Luo; Qi Zhao; Jian Ren; Zhixiang Zuo
• Keywords: 0301 basic medicine; 03 medical and health sciences; Reproducibility of Results; Software

Abstract

Summary MeRIPseqPipe is an integrated and automatic pipeline that can provide users a friendly solution to perform in-depth mining of MeRIP-seq data. It integrates many functional analysis modules, range from basic processing to downstream analysis. All the processes are embedded in Nextflow with Docker support, which ensures high reproducibility and scalability of the analysis. MeRIPseqPipe is particularly suitable for analyzing a large number of samples at once with a simple command. The final output directory is structured based on each step and tool. And visualization reports containing various tables and plots are provided as HTML files.

Availability and implementation MeRIPseqPipe is freely available at https://github.com/canceromics/MeRIPseqPipe.

Supplementary information Supplementary data are available at Bioinformatics online.