IslandPath: aiding detection of genomic islands in prokaryotes

• DOI: 10.1093/bioinformatics/btg004
• Publication Date: 2003-02-12T19:58:00Z
• Authors: William Hsiao; Ivan Wan; Steven J. Jones; Fiona S. L. Brinkman
• Keywords: 0303 health sciences; Bacteria; Gene Transfer, Horizontal; Sequence Analysis, DNA; Archaea; 03 medical and health sciences; Genome, Archaeal; Database Management Systems; CpG Islands; Sequence Alignment; Genome, Bacterial; Phylogeny; Software

Abstract Summary: Genomic islands (clusters of genes potential horizontal origin in a prokaryotic genome) are frequently associated with particular adaptation microbe that is medical, agricultural or environmental importance, such as antibiotic resistance, pathogen virulence, metal resistance. While many sequence features have been adopted separately applications for analysis genomic islands, including pathogenicity there no single application integrates multiple island detection. IslandPath network service which incorporates DNA signals and genome annotation into graphical display bacterial archaeal genome, to aid the detection islands. Availability: This available at http://www.pathogenomics.sfu.ca/islandpath source code freely available, under GNU public licence, from authors. Contact: [e-mail] Supplementary information: An online help file, includes analyses utility IslandPath, can be found http://www.pathogenomics.sfu.ca/islandpath/current/islandhelp.html * To whom correspondence should addressed.