DnaSP, DNA polymorphism analyses by the coalescent and other methods

• DOI: 10.1093/bioinformatics/btg359
• Publication Date: 2003-12-10T20:41:02Z
• Authors: Julio Rozas; Juan C. Sánchez-D...; Xavier Messeguer; Ricardo Rozas
• Keywords: :Informàtica::Aplicacions de la informàtica::Bioinformàtica [Àrees temàtiques de la UPC]; 0301 basic medicine; Programari; Polymorphism, Genetic; Gene Expression Profiling; Algorismes; ADN -- Anàlisi; Sequence Analysis, DNA; Expressió gènica; DnaSP (Computer program); User-Computer Interface; 03 medical and health sciences; DNA -- Analysis; Àrees temàtiques de la UPC::Informàtica::Aplicacions de la informàtica::Bioinformàtica; Expressió genètica; Gene expression; Sequence Alignment; Algorithms; Software

Abstract Summary: DnaSP is a software package for the analysis of DNA polymorphism data. Present version introduces several new modules and features which, among other options allow: (1) handling big data sets (∼5 Mb per sequence); (2) conducting a large number of coalescent-based tests by Monte Carlo computer simulations; (3) extensive analyses of the genetic differentiation and gene flow among populations; (4) analysing the evolutionary pattern of preferred and unpreferred codons; (5) generating graphical outputs for an easy visualization of results. Availability: The software package, including complete documentation and examples, is freely available to academic users from: http://www.ub.es/dnasp