A nearest-neighboring-end algorithm for genetic mapping

• DOI: 10.1093/bioinformatics/bti164
• Publication Date: 2004-11-26T01:13:24Z
• Authors: C. F. Crane; Y. M. Crane
• Keywords: Genetic Markers; 0303 health sciences; Models, Statistical; Models, Genetic; Genetic Linkage; DNA Mutational Analysis; Chromosome Mapping; 03 medical and health sciences; Genetics, Population; Humans; Computer Simulation; Algorithms; Gene Deletion; Software

Motivation: High-throughput methods are beginning to make possible the genotyping of thousands loci in individuals, which could be useful for tightly associating phenotypes candidate loci. Current mapping algorithms cannot handle so many data without building hierarchies framework maps.