A discrete view on fold space

• DOI: 10.1093/bioinformatics/btn020
• Publication Date: 2008-01-25T01:24:39Z
• Authors: Manfred J. Sippl; Stefan J. Suhrer; Markus Gruber; Markus Wiederstein
• Keywords: Models, Molecular; Protein Folding; 0303 health sciences; Molecular Sequence Data; Information Storage and Retrieval; Proteins; User-Computer Interface; 03 medical and health sciences; Models, Chemical; Sequence Analysis, Protein; Computer Simulation; Amino Acid Sequence; Databases, Protein; Algorithms; Software

Abstract Summary: The database of known protein structures contains an overwhelming number of structural similarities that frequently point to intriguing biological relationships. The similarities are often difficult to spot, and once detected their comprehension needs proper visualization. Here we introduce the new concept of a Fold Space Navigator, a user interface enabling the efficient navigation through fold space and the instantaneous visualization of pairwise structure similarities. Availability: The Fold Space Navigator is accessible as a public web service at http://services.came.sbg.ac.at Contact: [e-mail]