ISRNA: an integrative online toolkit for short reads from high-throughput sequencing data

• DOI: 10.1093/bioinformatics/btt678
• Publication Date: 2013-12-04T02:09:13Z
• Authors: Guan-Zheng Luo; Wei Yang; Ying-Ke Ma; Xiu-Jie Wang
• Keywords: Perl; Genome browser; Sequence (biology)

Abstract Summary: Integrative Short Reads NAvigator (ISRNA) is an online toolkit for analyzing high-throughput small RNA sequencing data. Besides the high-speed genome mapping function, ISRNA provides statistics genomic location, length distribution and nucleotide composition bias analysis of sequence reads. Number reads mapped to known microRNAs other classes short non-coding RNAs, coverage on genes, expression abundance as well some functions are also supported. The versatile search enable users select according their sub-sequences, abundance, relationship etc. A specialized browser integrated visualize supports management comparison among multiple datasets. Availability: implemented in Java/C++/Perl/MySQL can be freely accessed at http://omicslab.genetics.ac.cn/ISRNA/. Contact: [e-mail] Supplementary information: data available Bioinformatics online.