DiffGraph: an R package for identifying gene network rewiring using differential graphical models

• DOI: 10.1093/bioinformatics/btx836
• Publication Date: 2017-12-22T04:56:25Z
• Authors: Xiao-Fei Zhang; Le Ou-Yang; Shuo Yang; Xiaohua Hu; Hong Yan
• Keywords: R package; Software package; Gene regulatory network; Graphical user interface; Carry (investment)

Abstract Summary We develop DiffGraph, an R package that integrates four influential differential graphical models for identifying gene network rewiring under two different conditions from expression data. The input and output of are packaged in the same format, making it convenient users to compare using a wide range datasets carry out follow-up analysis. Furthermore, inferred networks can be visualized both non-interactively interactively. is useful datasets, comparing predictions methods visualizing results. Availability implementation available at https://github.com/Zhangxf-ccnu/DiffGraph. Supplementary information data Bioinformatics online.