ChronQC: a quality control monitoring system for clinical next generation sequencing

• DOI: 10.1093/bioinformatics/btx843
• Publication Date: 2017-12-27T12:20:22Z
• Authors: Nilesh R Tawari; Justine Jia Wen Seow; Dharuman Perumal; Jack L Ow; Shimin Ang; Arun George Devasia; Pauline C Ng
• Keywords: Python

ChronQC is a quality control (QC) tracking system for clinical implementation of next-generation sequencing (NGS). generates time series plots various QC metrics to allow comparison current runs historical runs. has multiple features data including Westgard rules validity, laboratory-defined thresholds and observations within specified period. Users can record their notes corrective actions directly onto the long-term recordkeeping. facilitates regular monitoring NGS enable adherence high standards.ChronQC freely available on GitHub (https://github.com/nilesh-tawari/ChronQC), Docker (https://hub.docker.com/r/nileshtawari/chronqc/) Python Package Index. implemented in all common operating systems (Windows, Linux Mac OS X)[e-mail] or [e-mail] are at Bioinformatics online.