Follicle Online: an integrated database of follicle assembly, development and ovulation

• DOI: 10.1093/database/bav036
• Publication Date: 2015-05-01T00:32:22Z
• Authors: J. Hua; B. Xu; Y. Yang; R. Ban; F. Iqbal; H. J. Cooke; Y. Zhang; Q. Shi
• Keywords: Ovulation; 0303 health sciences; Primary Ovarian Insufficiency; Online Systems; Rats; 3. Good health; Mice; 03 medical and health sciences; Ovarian Follicle; Databases, Genetic; Animals; Humans; Original Article; Cattle; Female; Polycystic Ovary Syndrome

Folliculogenesis is an important part of ovarian function as it provides the oocytes for female reproductive life. Characterizing genes/proteins involved in folliculogenesis fundamental understanding mechanisms associated with this biological and to cure diseases folliculogenesis. A large number have been identified from different species. However, no dedicated public resource currently available folliculogenesis-related that are validated by experiments. Here, we reporting a database ‘Follicle Online’ experimentally gene/protein map Follicle Online web-based system storing retrieving experimental data. It detailed information 580 (from 23 model organisms, including Homo sapiens, Mus musculus, Rattus norvegicus, Mesocricetus auratus, Bos Taurus, Drosophila Xenopus laevis ) reported be folliculogenesis, POF (premature failure) PCOS (polycystic ovary syndrome). The literature was manually curated more than 43 000 published articles (till 1 March 2014). implemented PHP + MySQL JavaScript user-friendly web application access stored In summary, developed centralized users comprehensive about This can accessed freely all data viewed without any registration. Database URL:http://mcg.ustc.edu.cn/sdap1/follicle/index.php